2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER
CAS: 59776-88-4
Molecular Formula: C7H11NO3
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER - Names and Identifiers
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER - Physico-chemical Properties
| Molecular Formula | C7H11NO3 |
| Molar Mass | 157.17 |
| Density | 1.131 g/mL at 25 °C (lit.) |
| Boling Point | 144-148℃ (16 Torr) |
| Flash Point | >230 °F |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Appearance | Oil |
| Color | Colourless |
| pKa | -1.01±0.20(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.472(lit.) |
| MDL | MFCD00003198 |
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R41 - Risk of serious damage to eyes R37/38 - Irritating to respiratory system and skin. R22 - Harmful if swallowed |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S39 - Wear eye / face protection. |
| WGK Germany | 3 |
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER - Upstream Downstream Industry
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER - Introduction
ACID METHYL ESTER is an organic compound with the chemical formula C7H11NO3. It is a colorless liquid with a special smell. The following is detailed information about its nature, use, formulation and safety information:
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents, insoluble in water
-Melting point: About -15 ° C
-Boiling point: about 145-155 ° C
-Density: approx. 1.12 g/mL
-Refractive index: about 1.463
Use:
ACID METHYL ESTER is often used as a reagent or experimental intermediate in organic synthesis. It can be used for the synthesis of pyrroline, β-lactam, furans and other organic compounds. In addition, it can also be used as a pharmaceutical intermediate for the synthesis of drugs or drug precursors.
Method:
The preparation method of ACID METHYL ESTER adopts esterification reaction. A common preparation method is to react 2-oxo-1-pyrrolidine acetic acid with methanol, add an acid catalyst, and heat the reaction to generate the target product.
Safety Information:
-acrylic METHYL ESTER may be irritating to the human body, causing eye, skin and respiratory tract irritation. Wear appropriate personal protective equipment, such as gloves, goggles and respirators.
-Avoid contact with fire or high temperature environment, because it is flammable.
-Storage should be kept away from fire and oxidant, and the storage temperature should be less than 30°C under inert gas.
-When using, pay attention to prevent inhalation, swallowing or contact with the skin, and clean the contaminated area in time when necessary.
Please note that the use and handling of chemicals should follow proper laboratory safety practices and personal protective measures. Before using any chemical, be sure to carefully read and follow the relevant safety data sheet (SDS) of the chemical.
Nature:
-Appearance: colorless liquid
-Solubility: Soluble in organic solvents, insoluble in water
-Melting point: About -15 ° C
-Boiling point: about 145-155 ° C
-Density: approx. 1.12 g/mL
-Refractive index: about 1.463
Use:
ACID METHYL ESTER is often used as a reagent or experimental intermediate in organic synthesis. It can be used for the synthesis of pyrroline, β-lactam, furans and other organic compounds. In addition, it can also be used as a pharmaceutical intermediate for the synthesis of drugs or drug precursors.
Method:
The preparation method of ACID METHYL ESTER adopts esterification reaction. A common preparation method is to react 2-oxo-1-pyrrolidine acetic acid with methanol, add an acid catalyst, and heat the reaction to generate the target product.
Safety Information:
-acrylic METHYL ESTER may be irritating to the human body, causing eye, skin and respiratory tract irritation. Wear appropriate personal protective equipment, such as gloves, goggles and respirators.
-Avoid contact with fire or high temperature environment, because it is flammable.
-Storage should be kept away from fire and oxidant, and the storage temperature should be less than 30°C under inert gas.
-When using, pay attention to prevent inhalation, swallowing or contact with the skin, and clean the contaminated area in time when necessary.
Please note that the use and handling of chemicals should follow proper laboratory safety practices and personal protective measures. Before using any chemical, be sure to carefully read and follow the relevant safety data sheet (SDS) of the chemical.
Last Update：2024-04-09 15:18:03
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Product Name: 2-Oxo-1-Pyrrolidineacetic Acid Methyl Ester Visit Supplier Webpage Request for quotation
CAS: 59776-88-4
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View History
2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER
叔丁基二甲基甲氧基硅烷
BOC-氨基-单乙二醇-羧酸
鹅掌楸树脂酚B二甲醚
TIMTEC-BB SBB011106
DIETHYL 2-CYANO-3-OXOSUCCINATE
1-异丙氨基-3-(1-萘氧基)-2-丙醇盐酸盐
2-(二甲胺基)-2-氧代乙基 2-(4-羟基苯基)乙酸酯
1,4-PHENYLENEBIS(BORONIC ACID)
D-Mannonic acid, 2,6-anhydro-, delta-lactone (9CI)
叔丁基二甲基甲氧基硅烷
BOC-氨基-单乙二醇-羧酸
鹅掌楸树脂酚B二甲醚
TIMTEC-BB SBB011106
DIETHYL 2-CYANO-3-OXOSUCCINATE
1-异丙氨基-3-(1-萘氧基)-2-丙醇盐酸盐
2-(二甲胺基)-2-氧代乙基 2-(4-羟基苯基)乙酸酯
1,4-PHENYLENEBIS(BORONIC ACID)
D-Mannonic acid, 2,6-anhydro-, delta-lactone (9CI)
Raw Materials for 2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER
Acetic acid, 2-[(3,4-dihydro-2H-pyrrol-5-yl)oxy]-, methyl ester
1-TRIMETHYLSILYL-2-PYRROLIDINONE
METHYL DIAZOACETATE
Methyl bromoacetate
2-Pyrrolidinone
1-TRIMETHYLSILYL-2-PYRROLIDINONE
METHYL DIAZOACETATE
Methyl bromoacetate
2-Pyrrolidinone
Downstream Products for 2-OXO-1-PYRROLIDINEACETIC ACID METHYL ESTER